Cancer treatments with radiation and immunocytokines

A - Human Necessities – 61 – K

Patent

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A61K 38/20 (2006.01)

Patent

CA 2741130

The present invention is directed to a method for treating tumors and cancer cells by administering an immunocytokine following radiation treatment. This combination of treatments can stimulate an immune response at irradiated and non-irradiated sites, which is useful in eradicating cancer cells that have spread from the site of the primary tumor. In addition, immunocytokines can be administered at a dose that is less that the maximum tolerated dose, which reduces the side effects associated with immunocytokine therapy.

La présente invention concerne un procédé pour traiter des tumeurs et des cellules cancéreuses par administration dune immunocytokine après traitement par rayonnement. Cette combinaison de traitements peut stimuler une réponse immunitaire à des sites irradiés et non irradiés, qui est utile dans léradication de cellules cancéreuses qui se sont propagées depuis le site de la tumeur primaire. De plus, des immunocytokines peuvent être administrées à une dose qui est inférieure à la dose maximale tolérée, ce qui réduit les effets secondaires associés à une thérapie avec des immunocytokines.

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