Cancer vaccines and methods of using the same

Details Cancer vaccines and methods of using the same Cancer vaccines and methods of using the same

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 39/00 (2006.01) A61P 37/04 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2484266

The invention discloses cancer vaccines comprising lipid-nucleic acid formulations in combination with one or more tumor-associated antigens which are capable of stimulating strong, Th-1 biased cellular immune responses to said tumor-associated antigens in vivo. It is further disclosed the subject cancer vaccines provide therapeutic efficacy in treating tumors in an animal.

L'invention concerne des vaccins contre le cancer, qui comprennent des préparations de lipide et d'acide nucléique associés à un ou plusieurs antigènes spécifiques de tumeurs. Ces vaccins peuvent stimuler in vivo de puissantes réponses immunitaires à médiation cellulaire induites par Th-1 auxdits antigènes spécifiques de tumeurs. Les vaccins contre le cancer, objets de l'invention, sont en outre efficaces pour le traitement de tumeurs chez un animal.

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