C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/18 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 5/16 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2675292
The present invention relates to a method for producing cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, cytokines, interferons, target or reporter moieties and hematogenous cells.
La présente invention concerne un procédé permettant de produire des anticorps modifiant une maladie cancéreuse à l'aide d'un nouveau paradigme de criblage. La ségrégation d'anticorps anticancéreux faisant appel à la cytotoxicité des cellules cancéreuses en tant que point d'aboutissement permet de produire ces anticorps anticancéreux à des fins thérapeutiques et diagnostiques. On peut utiliser les anticorps pour contribuer à la classification par stade et au diagnostic d'un cancer, et pour le traitement de tumeurs primaires et de métastases tumorales. Lesdits anticorps anticancéreux peuvent être conjugués à des toxines, des enzymes, des composés radioactifs, des cytokines, des interférons, des fragments cibles ou rapporteurs et des cellules hématogènes.
Findlay Helen P.
Hahn Susan E.
Popp Lisa A.
Young David S. F.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
LandOfFree
Cancerous disease modifying antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cancerous disease modifying antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cancerous disease modifying antibodies will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1796593