Cancerous metastasis-associated gene

Details Cancerous metastasis-associated gene Cancerous metastasis-associated gene

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2286038

A gene exhibiting stronger expression in mouse IMC-HM cells than in mouse IMC- LM cells and isolated by using the differential display method. When the relation between the expression of the isolated gene and cancerous metastasis is examined, it is found out that a transformant with the larger expression dose of the antisense mRNA to the gene shows the more lowered cancerous metastasis ability. By using the isolated protein, cancerous metastasis inhibitors can be screened.

Cette invention a pour objet un gène qui présente une expression plus forte dans des cellules IMC-HM de souris que dans des cellules IMC-LM de souris, ce gène ayant été isolé au moyen du procédé de présentation différentielle. Quand on examine la relation entre l'expression du gène isolé et la métastase cancéreuse on remarque qu'un transformant ayant la dose d'expression la plus forte de l'ARNm non codant pour le gène montre l'aptitude la plus réduite pour la métastase cancéreuse. A l'aide de la protéine isolée on peut cribler des inhibiteurs de métastase cancéreuse.

Affiliated with

Also associated with

Rating

Cancerous metastasis-associated gene does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cancerous metastasis-associated gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cancerous metastasis-associated gene will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1519640