C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/50 (2006.01) A61K 39/215 (2006.01) C07K 14/165 (2006.01) C12N 9/16 (2006.01) C12N 15/55 (2006.01)
Patent
CA 2492333
A canine respiratory coronavirus (CRCV) that is present in the respiratory tract of dogs with canine infectious respiratory disease and which has a low level of homology to the enteric canine coronavirus, but which has a high level of homology to all bovine coronavirus strains (eg Quebec and LY138) and human coronavirus strain OC43. The CRCV spike, polymerase and hemagglutinin/esterase cDNA and protein partial sequences are listed in Figures (1) to (4), (13) and (14).
La présente invention concerne un coronavirus respiratoire canin (CRCV) qui est présent dans les voies respiratoires de chiens atteints d'une maladie respiratoire infectieuse canine et qui a un niveau d'homologie faible au coronavirus entérique canin, mais a un niveau d'analogie élevé à tous les brins du coronavirus bovin (par ex. Quebec et LY138) et au brin de coronavirus humain OC43. Dans les figures (1) à (4), (13) et (14) sont listés l'ADNc de la protéine à pointes (spike protein) du CRCV, de la polymérase et de l'hémagglutinine/estérase correspondantes, et des séquences protéiques partielles.
Brownlie John
Chalker Victoria Jane
Erles Kerstin
Borden Ladner Gervais Llp
The Royal Veterinary College
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