Canine specific growth hormone releasing hormone

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) A61K 38/25 (2006.01) A61K 48/00 (2006.01) C07K 14/60 (2006.01) C12N 15/16 (2006.01)

Patent

CA 2575926

A composition and a method of increasing growth hormone ("GH") values in a canine or dog, and more specifically, a canine- or dog- specific growth hormone releasing hormone ("dGHRH"), or functional biological equivalent thereof. The dGHRH is an isolated composition or a nucleic acid molecule that encodes the dGHRH or functional biological equivalent. Also, a method for delivering the composition of this invention to a subject, wherein the dGHRH increases the level of growth hormone ("GH") secretion in a recipient subject, such as a canine or dog.

La présente invention concerne une composition et un procédé permettant d'accroître des valeurs d'hormones de croissance (GH) chez un chien ou un animal canin et, plus spécifiquement, une hormone libérant une hormone de croissance spécifique du chien ("dGHRH"), ou un équivalent biologique fonctionnel de celle-ci. Cette hormone dGHRH est une composition isolée ou une molécule d'acide nucléique codante pour cette hormone dGHRH ou cet équivalent biologique fonctionnel. Cette invention concerne aussi une technique d'apport de la composition de cette invention à un sujet, l'hormone dGHRH augmentant le niveau de sécrétion d'hormones de croissance (GH) chez ce sujet, tel qu'un animal canin ou un chien.

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