Canine thymic stromal lymphopoietin protein and uses thereof

Details Canine thymic stromal lymphopoietin protein and uses thereof Canine thymic stromal lymphopoietin protein and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/54 (2006.01) A61K 38/20 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2671865

The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific epitopes of the canine TSLP protein are also disclosed. The canine TSLP protein and related peptide fragments may be used as an antigen for immunological assays, as well as for vaccines that induce anti-TSLP antibodies. The present invention further discloses methods of making and using the canine TSLP gene, the canine TSLP protein, and the related peptide fragments.

La présente invention concerne une protéine TSLP canine et un acide nucléique codant pour cette protéine. L'invention concerne également des fragments peptidiques de ladite protéine renfermant des épitopes spécifiques de la protéine TSLP canine. Cette protéine TSLP canine et les fragments peptidiques associés peuvent être utilisés comme antigène pour des dosages immunologiques et pour des vaccins induisant des anticorps anti-TSLP. L'invention concerne également des méthodes de production et d'utilisation du gène de la TSLP canine, de la protéine TSLP canine et des fragments peptidiques associés.

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