Canine tumor treatment method, pharmaceutical formulation...

Details Canine tumor treatment method, pharmaceutical formulation... Canine tumor treatment method, pharmaceutical formulation...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 35/14 (2006.01) A61K 38/20 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2556473

A treatment for tumorous canines and a method of preparing, cultivating, and cryogenically preserving the pharmaceutical formulation used in the treatment. Canine lymphocytes are activated and expanded in the presence of a combination of anti-canine CD3 antibodies and interleukin-2 (IL-2) (preferably anti-canine CD3 antibodies and human interleukin-2 (human IL-2)) and administered to tumorous dogs. Following treatment, the canine tumors were observed to be in regression while no serious side effects were noted. Quality-of-life improvements were observed in the form of the animals' ability to walk increased distances and improved coat appearance.

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