Cannabinoid receptor antagonists/inverse agonists useful for...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 231/06 (2006.01) A61K 31/415 (2006.01) A61P 1/16 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2702755

The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, hepatic disorders, and/or cardiometabolic disorders.

La présente invention concerne des pyrazoles inédits pouvant être utilisés en tant qu'antagonistes des récepteurs aux cannabinoïdes, ainsi que des compositions pharmaceutiques en contenant. L'invention concerne également des procédés d'utilisation desdites compositions pharmaceutiques en vue du traitement de l'obésité, du diabète, de troubles hépatiques et/ou de troubles cardiométaboliques.

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