Cannabinol derivatives and improved immunoassay

C - Chemistry – Metallurgy – 07 – D

Patent

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195/35, 167/45,

C07D 311/94 (2006.01) G01N 33/535 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1293213

ABSTRACT Novel cannabinol derivatives are provided which can be used in improved immunoassays for the detection in blood or urine samples of cannabinol metabolites. The novel cannabinol derivatives are of the formula: Image where R is an attachment chain selected from the group consisting of a p-aminobenzyl group or a branched or linear aminoalkyl group having from 1 to 7 carbon atoms or an organic or mineral acid addition salt thereof, an isocyanate or isothiocyanate derivative of the p-aminobenzyl or aminoalkyl group, a carboxyl terminated derivative of the aminoalkyl group having from 1 to 7 carbon atoms or a salt thereof, and an activated derivative of the carboxyl terminated derivative.

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