Capillary array-based sample screening

Details Capillary array-based sample screening Capillary array-based sample screening

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) B01J 19/00 (2006.01) B01L 3/00 (2006.01)

Patent

CA 2360750

Provided are methods of screening and identification of bioactivities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical detection and capillary array-based techniques for screening libraries and recovering bioactive molecules having a desired activity or a nucleic acid sequence encoding such bioactive molecules.

Cette invention a trait à des techniques de criblage et d'identification d'activités biologiques et de molécules bioactives, lesquelles techniques font intervenir un système en rangées de capillaires. Elle porte, plus précisément, sur des techniques faisant appel à la détection optique ainsi que sur des techniques utilisant des systèmes en rangées de capillaires aux fins du criblage de bibliothèques et de la récupération de molécules bioactives dotées d'une activité souhaitée ou d'une séquence nucléotidique les codant.

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