A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/21 (2006.01) A61K 35/14 (2006.01) C07K 14/155 (2006.01) C12N 7/00 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2249736
The present invention provides a vaccine comprising a caprine arthritis- encephalitis virus (CAEV) immunogen and a pharmaceutically acceptable carrier. The invention also provides a method of stimulating an immune response in an individual against human immunodeficiency virus-1 infection or against CAEV infection by administering a therapeutically effective amount of a CAEV immunogen to the individual. The invention further provides a method of stimulating an immune response in vitro by contacting a lymphocyte with a therapeutically effective amount of a CAEV immunogen. Methods of diagnosing CAEV infection in humans are also provided.
L'invention porte sur un vaccin comportant un immunogène du virus de l'arthrite/encéphalite caprine (CAEV) et ses supports pharmacocompatibles. Elle porte également sur un procédé de stimulation de la réponse immunitaire d'un individu vis à vis d'une infection due au VIH-1, ou vis à vis d'une infection due au virus du CAEV consistant à administrer à un individu une dose à effet thérapeutique d'un immunogène du CAEV. L'invention porte en outre sur un procédé de stimulation de la réponse immunitaire in vitro consistant à mettre en contact un lymphocyte avec une dose à effet thérapeutique d'un immunogène du CAEV, et sur des méthodes permettant de diagnostiquer chez l'homme des infections dues au CAEV.
Douvas Angeline
Ehresmann Glenn
Smart & Biggar
The University Of Southern California
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