Capsular polysaccharide immunomodulator

Details Capsular polysaccharide immunomodulator Capsular polysaccharide immunomodulator

A - Human Necessities

61

K

A61K 39/02 (2006.01) A61K 39/114 (2006.01) A61K 39/116 (2006.01)

Patent

CA 2197563

Methods and products for protecting against abscess formation associated with surgery, trauma or diseases that predispose the host to abscess formation are provided. Methods for forming immunomodulators and pharmaceutical compositions relating thereto are also provided. The products useful in the invention are polysaccharides including a repeat unit having a positively charged free amino group and a negatively charged group. The preferred polysaccharide is B.fragilis capsular polysaccharide A.

L'invention concerne des procédés et des produits destinés à protéger contre la formation d'abcès associée à la chirurgie, aux traumatismes ou aux maladies qui prédisposent l'hôte à la formation d'abcès. L'invention concerne également des procédés pour former des immunomodulateurs et des compositions pharmaceutiques s'y rapportant. Les produits utiles dans l'invention sont des polysaccharides renfermant un motif récurrent possédant un groupe amino libre à charge positive et un groupe à charge négative. Le polysaccharide préféré est le polysaccharide A capsulaire B. fragilis.

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