Capsule formulation of pirfenidone and pharmaceutically...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/48 (2006.01) A61K 9/16 (2006.01) A61K 9/28 (2006.01) A61K 31/4412 (2006.01)

Patent

CA 2620380

A capsule formulation of pirfenidone is provided that includes pharmaceutically acceptable excipients. In one embodiment, this capsule formulation is capable of sustaining desirable pharmacokinetic responses in a patient. Further provided are methods of treating fibrotic conditions and other cytokine-mediated disorders by administering pirfenidone capsules of such formulation to a patient in need.

L'invention porte sur la formule de capsules de pirfénidone comprenant des excipients pharmacocompatibles. Dans une exécution la formule produit les effets pharmacocinétiques continus désirables chez un patient. L'invention porte également sur des méthodes de traitement d'états fibrotiques et autres troubles médiés par la cytokine par administration de telles capsules.

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