C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/154, 117/45
C12N 11/02 (2006.01) A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01) B01J 13/08 (2006.01) B01J 13/20 (2006.01) C12N 5/00 (2006.01) C12N 5/16 (2006.01)
Patent
CA 1238273
Abstract of the Disclosure Disclosed is an improved process for encapsulating core materials, particularly viable cells, within a membrane of controlled porosity. A polyanionic polymer, e.g., sodium alginate, is formed into shape-retaining gel masses. The gelled masses are then expanded by hydration, and a membrane is formed by reaction at the surface of the expanded masses with a polyanionic polymer having a molecular weight greater than 3000. The expansion step promotes the formation of continuous, uniform capsule membranes of more consistent permeability resulting in a more reproducible cell encap- sulation process.
473751
Shyr Ann W.
Tsang Wen-Ghih
Damon Biotech Inc.
Riches Mckenzie & Herbert Llp
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