Capsule pharmaceutical dosage form comprising a suspension...

A - Human Necessities – 61 – K

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Details

A61K 9/48 (2006.01) A61K 9/10 (2006.01) A61K 31/404 (2006.01) A61K 47/14 (2006.01) A61K 47/24 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2726267

The present invention relates to a suspension formulation containing the active substance 3-Z-[1-(4-(N-((4-methyl--piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)- anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone-monoethane-- sulphonate, to a capsule pharmaceutical dosage form containing said suspension formulation, to a process for preparing said sus-pension formulation, to a process for preparing said capsule comprising said suspension formulation and to the packaging material for the finished capsule.

La présente invention concerne une formulation en suspension dont le principe actif est le 3-Z-[1-(4- (N-((4-méthyl-pipérazin-1-yl)-méthylcarbonyl)-N-méthyl-amino)-anilino)-1-phényl-méthylène]-6- méthoxycarbonyl-2- indolinone-monoéthane-sulphonate. L'invention concerne également, d'une part une forme posologique pharmaceutique en capsule contenant ladite formulation en suspension, d'autre part un procédé d'élaboration de ladite formulation en suspension, mais aussi un procédé d'élaboration de ladite capsule comprenant ladite formulation en suspension, et également le matériau d'enveloppe de la capsule.

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