Carba-nucleoside analogs for antiviral treatment

Details Carba-nucleoside analogs for antiviral treatment Carba-nucleoside analogs for antiviral treatment

C - Chemistry, Metallurgy

07

H

C07H 19/24 (2006.01) A61K 31/7064 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2751277

Provided are thieno[3,4-d]pyrimidin-7-yl and furo[3,4-d]pyrimidin-7-yl ribosides, riboside phosphates and prodrugs thereof as well as intermediates and methods of preparation. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections.

L'invention concerne des thiéno[3,4-d]pyrimidin-7-yI et furo[3,4-d]pyrimidin-7-yl ribosides, des phosphates de riboside et des promédicaments correspondants, ainsi que des intermédiaires et des procédés d'élaboration. Les composés, compositions, et procédés décrits sont utiles pour le traitement des infections virales à Flaviviridae.

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