Carba-sugar amine derivative and glycolipid metabolic...

C - Chemistry – Metallurgy – 07 – C

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C07C 215/44 (2006.01) A61K 31/13 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01) C07C 271/24 (2006.01)

Patent

CA 2459887

A carba-sugar amine derivative represented by the following formula (1) or (2) is used as the active ingredient of a .beta.-galactosidase inhibitor or a glycolipid metabolic disorder treating agent. (see formula 1) (see formula 2) wherein each of R1 and R2 independently represents H, an alkyl group, an acyl group, an aryl group or an aralkyl group, with the proviso that both are not H at the same time, and each of R3, R4, R5 and R6 independently represents a hydroxyl group or hydroxyl group having a substituent. Also, R7 represents an alkyl group, and each of R8, R9, R10 and R11 independently represents a hydroxyl group or a hydroxyl group having a substituent.

L'invention concerne des dérivés de carba-sucres amine représentés par la formule générale (1) ou (2), qui peuvent servir comme ingrédients actifs des inhibiteurs .beta.-galactosidase ou agents de traitement du trouble du métabolisme des glycolipides, dans lesquelles R?1¿ et R?2¿ représentent chacun indépendamment H, alkyle, acyle, aryle ou aralkyle, pour autant que les deux ne soient pas hydrogène; R?3¿, R?4¿, R?5¿ et R?6¿ représentent chacun indépendamment hydroxyle ou hydroxyle substitué; (R7) représente alkyle; et R?8¿, R?9¿, R?10¿ et R?11¿ représentent chacun indépendamment hydroxyle ou hydroxyle substitué.

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