Carbamate compounds for use in preventing or treating...

A - Human Necessities – 61 – K

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A61K 31/27 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01)

Patent

CA 2439286

This invention is directed to a method for preventing or treating anxiety disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group consisting of Formula (I) and Formula (II): Formula (I); Formula (II); wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3, R4, R5 and R6 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).

L'invention concerne un procédé de prévention ou de traitement de troubles anxieux consistant à administrer à un sujet une quantité thérapeutiquement efficace d'un composant sélectionné à partir du groupe de formule (I) et de formule (II) : formule (I); formule (II); où le phényl est remplacé à X par un à cinq atome(s) halogène sélectionné(s) dans le groupe composé de fluor, chlore, brome et iode; et R¿1?, R¿2?, R¿3?, R¿4?, R¿5? et R¿6? sont sélectionnés de manière indépendante à partir du groupe composé d'hydrogène et d'alkyle C¿1?-C¿4?; dans lequel l'alkyle C¿1?-C¿4? est éventuellement remplacé par le phényl (dans lequel le phényl est éventuellement remplacé par des éléments de remplacement sélectionnés de manière indépendante à partir du groupe composé d'halogène, alkyle C¿1?-C¿4?, alcoxy C¿1?-C¿4?, amino, nitro et cyano).

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