Carbamate derivatives of 4-amino-3- isoxazolidinones,...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/40 (2006.01) A61K 31/55 (2006.01) C07D 491/06 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2079548

Carbamate Derivatives of 4-Amino-3-isoxazolidinones, 3-Amino-1-hydroxypyrrolidin-2-ones and 1-Amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments (see formula I) where R1 is (see formulas II, III or IV) and R2 is (see formulas V, VI or VII) and to a process for their preparation. The compounds are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease.

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