Carbamate derivatives of alkyl-heterocycles, preparation...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 401/14 (2006.01) A61K 31/445 (2006.01) A61K 31/4709 (2006.01) A61K 31/497 (2006.01) A61K 31/498 (2006.01) A61K 31/501 (2006.01) A61K 31/502 (2006.01) A61K 31/506 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 403/14 (2006.01) C07D 407/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2743558

Compound corresponding to general formula (I): in which R2 is a hydrogen or fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6- alkoxy or NR8R9 group; n is an integer equal to 1, 2 or 3 and m is an integer equal to 1 or 2; A is a covalent bond or a C1-8-alkylene group; R1 is a phenyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, triazinyl, naphthyl, quinolinyl, isoquinolinyl, phthalazinyl, quinazolinyl, quinoxalinyl, cinnolinyl or naphthyridinyl group, this group being optionally substituted; R3 is a hydrogen or fluorine atom, a C1-6-alkyl group or a trifluoromethyl group; R4 is a group selected from furanyl, pyrrolyl, thienyl, isothiazolyl, oxazolyl, isoxazolyl, pyrazolyl, oxadiazolyl, thiadiazolyl, imidazole, triazolyl, tetrazolyl, oxazolone, oxazolidinone, isoxazolone, isoxazolidinone, isothiazolone, isothiazolidinone, imidazolone, imidazolidinone, pyrazolone, pyrazolidinone, oxadiazolone, thiadiazolone and triazolone, this group being optionally substituted; in the form of a base or of an addition salt with an acid. Therapeutic use.

Image Composé répondant à la formule (I) dans laquelle R2 représente un atome d'hydrogène, de fluor ou un groupe hydroxyle, cyano, trifluorométhyle, C1-6-alkyle, C1-6- alcoxy, NR8R9; n représente un nombre entier égal à 1, 2 ou 3 et m représente un nombre entier égal à 1 ou 2; A représente une liaison covalente ou un groupe C1-8-alkylène; R1 représente un groupe phényle, pyridinyle, pyridazinyle, pyrimidinyle, pyrazinyle, triazinyle, naphtalènyle, quinolinyle, isoquinolinyle, phtalazinyle, quinazolinyle, quinoxalinyle, cinnolinyle, naphthyridinyle, ce groupe étant éventuellement substitué; R3 représente un atome d'hydrogène, de fluor, un groupe C1-6-alkyle ou un groupe trif luorométhyle; R4 représente un groupe choisi parmi un furanyle, pyrrolyle, thiènyle, isothiazolyle, oxazolyle, isoxazolyle, pyrazolyle, oxadiazolyle, thiadiazolyle, imidazole, triazolyle, tétrazolyle, oxazolone, oxazolidinone, isoxazolone, isoxazolidinone, isothiazolone, isothiazolidinone, imidazolone, imidazolidinone, pyrazolone, pyrazolidinone, oxadiazolone, thiadiazolone, triazolone, ce groupe étant éventuellement substitué; à l'état de base ou de sel d'addition à un acide. Application en thérapeutique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Carbamate derivatives of alkyl-heterocycles, preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbamate derivatives of alkyl-heterocycles, preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbamate derivatives of alkyl-heterocycles, preparation... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1701252

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.