Carbamate derivatives, process for their preparation and...

Details Carbamate derivatives, process for their preparation and... Carbamate derivatives, process for their preparation and...

A - Human Necessities

61

K

260/468

A61K 31/325 (2006.01)

Patent

CA 1220218

Abstract The invention relates to new carbamyloxy- benzhydrol derivatives of the formula (I) Image (I) wherein R1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms; R2 is hydrogen or an R3-NH-COO- group; R3 is alkyl having from one to 6 carbon atoms, cycloalkyl having up to 7 carbon atoms, or phenyl 9 optionally substituted with one or more halogen(s). The compounds of the formula (I) show anti- lipaemic activity and can therefore be used in therapy for treating hyperlipaemia and coronary diseases. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.

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