Carbamazepine medicament with retarded active substance release

Details Carbamazepine medicament with retarded active substance release Carbamazepine medicament with retarded active substance release

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 31/551 (2006.01)

Patent

CA 2194216

An oral administration carbamazepine medicament with a retarded active substance release is disclosed. An aqueous plasticised polymer dispersion is applied on carbamazepine crystals without causing formation of carbamazepine dihydrate. The carbamazepine crystals with their aqueous coating may be mixed with appropriate auxiliary substances, shaped into divisible tablets or filled into capsules.

L'invention concerne un médicament à la carbamazépine à administration orale et à libération retardée du principe actif. On applique une dispersion aqueuse de polymère plastifié sur les cristaux de carbamazépine sans qu'il y ait formation de dihydrate de carbamazépine. On peut mélanger les cristaux de carbamazépine enduits de dispersion aqueuse avec des substances auxiliaires appropriées, les transformer en comprimés sécables ou en remplir des capsules.

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