Carbamoyloxy derivatives of mutiline and their use as...

C - Chemistry – Metallurgy – 07 – C

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C07C 271/32 (2006.01) A61K 31/27 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07C 271/36 (2006.01) C07C 271/60 (2006.01) C07C 271/64 (2006.01) C07C 271/66 (2006.01) C07C 281/02 (2006.01) C07C 307/06 (2006.01) C07C 311/08 (2006.01) C07C 311/39 (2006.01) C07C 311/47 (2006.01) C07C 311/53 (2006.01) C07C 317/44 (2006.01) C07C 323/60 (2006.01) C07C 331/14 (2006.01) C07D 203/08 (2006.01) C07D 203/20 (2006.01) C07D 207/16 (2006.01) C07D 209/08 (2006.01) C07D 209/4

Patent

CA 2240467

Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the treatment of bacterial infections.

Dérivés de mutiline représentés par la formule (1A), ainsi que leurs sels et dérivés pharmaceutiquement acceptables, dans laquelle R?1¿ représente éthyle ou vinyle, Y représente un groupe carbamoyloxy, dans lequel l'atome N est non substitué, ou mono ou di-substitué. Ces composés sont utiles dans le traitement d'infections bactériennes.

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