Carbamoyloxyisoxazole derivatives, their preparation and...

C - Chemistry – Metallurgy – 07 – D

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260/311.9

C07D 261/12 (2006.01) A01N 47/18 (2006.01)

Patent

CA 1160236

ABSTRACT Compounds of formula (I): Image (I) (wherein: R1 represents a hydrogen atom or a halogen atom; R2 represents a C1-C6 alkyl group; and A represents an oxygen atom, a sulphur atom, a sulphlnyl group or a sulphonyl group) have good insecticidal activity coupled with a low toxicity to warm-blooded animals. Compounds in which A represents an oxygen or sulphur atom can be prepared by reacting a corresponding alkali metal alkoxide or mercaptide with the correspond1ng 3-dimethylcarbamoyloxy-5-halomethyl- isoxazole derivative, whilst compounds where A represents a sulphinyl or sulphonyl group may be prepared by oxidizing the corresponding compound wherein A represents a sulphur atom. The compounds may be formulated with conventional insecticidal carriers or diluents and exhibit a synergistic increase in activity when combined with various known organic phosphate and carbamate insecticides.

389795

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