Carbapenem antibacterial compounds, compositions and methods...

Details Carbapenem antibacterial compounds, compositions and methods... Carbapenem antibacterial compounds, compositions and methods...

C - Chemistry, Metallurgy

07

D

C07D 477/14 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2306565

Compounds of formula (I) are disclosed as well as pharmaceutically acceptable salts thereof. The naphthosultam is substituted with various substituent groups including at least one cationic group -A-Q-L-B. The carbapenems of the invention are effective against susceptible bacterial organisms, including methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and methicillin resistant coagulase negative Staphylococci (MRCNS).

L'invention concerne des composés correspondant à la formule (I) ainsi que les sels pharmaceutiquement acceptables de ces composés. Le naphtosultame est substitué par divers groupes dont au moins un groupe cationique -A-Q-L-B. Les carbapénèmes de l'invention sont efficaces contre les organismes bactériens sensibles, dont le staphylocoque doré résistant à la méthicilline, le staphylocoque epidermidis résistant à la méthicilline et les staphylocoques à coagulase négative résistant à la méthicilline.

Affiliated with

Also associated with

Rating

Carbapenem antibacterial compounds, compositions and methods... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbapenem antibacterial compounds, compositions and methods..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbapenem antibacterial compounds, compositions and methods... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1478429