C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/187, 260/299
C07D 487/04 (2006.01) A61K 31/40 (2006.01) C07D 477/20 (2006.01)
Patent
CA 1305709
ABSTRACT OF THE DISCLOSURE Carbapenem derivatives useful as antibacterial agents have the formula Image (I) wherein: X represents a hydrogen atom or a methyl group and Y represents a group of the formula: Image Image Image or in which: Z represents an oxygen atom or two hydrogen atoms; R1 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkanoyl group, or a C1-4 alkanesulfonyl group; R2 represents a hydrogen atom or a hydroxy group, and R3 represents a carbamoyl group: or R2 represents a carbamoyloxy group, and R3 represents a hydrogen atom or a carbamoyl group; R4 represents a hydrogen atom or a C1-4 alkyl group; and Image represents a 4-6 membered saturated heterocyclic group in which the indicated nitrogen atom is the only hetero-atom; or a pharmaceutically acceptable salt or ester thereof.
507751
Endo Rokuro
Iwata Masayuki
Kawamoto Isao
Endo Rokuro
Iwata Masayuki
Kawamoto Isao
Marks & Clerk
Sankyo Company Limited
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