Carbapenem derivatives and antimicrobials

Details Carbapenem derivatives and antimicrobials Carbapenem derivatives and antimicrobials

C - Chemistry, Metallurgy

07

D

C07D 519/06 (2006.01) A61K 31/425 (2006.01) C07D 477/20 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2244123

Compounds exhibiting a wide and potent antimicrobial activity against gram- positive and gram-negative bacteria, a potent antimicrobial activity against various .beta.-lactamase producing bacteria, MRSA and resistant Pseudomonas aeruginosa, and an extremely high stability to DHP-I. The compounds are presented by general formulae (I) and (II).

L'invention porte sur des composés exerçant une puissante activité anti-microbienne sur les bactéries gram-positives et gram-négatives, et une puissante activité anti-microbienne sur différentes bactéries productrices de .beta.-lactamase, sur le MRSA, et sur les Pseudomonas aeruginosa résistants, tout en présentant une stabilité extrêmement élevée vis à vis du DHP-I. Lesdits composés sont représentés par les formules générales (I) et (II).

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