C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/242, 260/299
C07D 487/04 (2006.01) C07D 213/32 (2006.01) C07D 249/04 (2006.01) C07D 249/08 (2006.01) C07D 257/04 (2006.01) C07D 285/06 (2006.01) C07D 477/20 (2006.01) C07F 9/6561 (2006.01)
Patent
CA 1273010
ABSTRACT Disclosed is a new and more efficient process for producing carbapenem antibiotic derivatives having a 2- substituent of the general formula Image in which A represents a C1-C6 straight or branched chain alkylene group; R5 represents an optionally substituted aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aryl, araliphatic, heteroaryl, heteroaraliphatic, heterocyclyl or heterocyclyl-aliphatic radical; and Image represents a nitrogen-containing aromatic heterocycle attached to the alkylene group A at a ring carbon atom and quaternized by substituent R5.
461853
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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