Carbapenem process

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) C07D 213/20 (2006.01) C07D 213/30 (2006.01) C07D 213/65 (2006.01) C07D 213/70 (2006.01) C07D 213/73 (2006.01) C07D 233/84 (2006.01) C07D 295/088 (2006.01) C07D 477/02 (2006.01)

Patent

CA 1284324

ABSTRACT Disclosed is a new and more efficient process for producing carbapenem antibiotic derivatives having a 2- substituent of the general formula S-A-R14 wherein A represents cyclopentylene, cyclohexylene or C2-C6 alkylene optionally substituted by one or more C1-C4 alkyl groups and R14 represents a quaternized nitrogen-containing aromatic or non-aromatic heterocycle attached to A through a quaternary nitrogen atom.

448904

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