Carbazole derivatives and their use as npy5 receptor...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/437 (2006.01) A61P 3/04 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2459973

The use of a compound of formula (I) in the manufacture of a medicament for the treatment, in a warm-blooded animal, of disorders mediated by the neuropeptide Y5 receptor (I), wherein: R1, R2, R3 and X1-X6 are as defined within or a pharmaceutically acceptable salt, prodrug or solvate thereof, is described. Pharmaceutical compositions, methods and processes for preparation of compounds of formula (I) are also described.

L'invention concerne un composé de formule (I), dans laquelle R¿1?, R¿2?, R¿3? et X?1¿-X?6¿ sont tels que définis dans la description, ou un sel, un promédicament ou un solvate pharmaceutiquement acceptable de ce composé, ainsi que leur utilisation pour fabriquer un médicament pour traiter, chez un animal à sang chaud, des troubles induits par le récepteur du neuropeptide Y5. L'invention concerne également des compositions pharmaceutiques, des méthodes et des procédés pour préparer des composés de formule (I).

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