Carbocyclic adenosine analogs useful as immunosupressants

Details Carbocyclic adenosine analogs useful as immunosupressants Carbocyclic adenosine analogs useful as immunosupressants

C - Chemistry, Metallurgy

07

D

C07D 473/00 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2051012

This invention relates to novel carbocyclic adenosine compounds of the formula (1) Image wherein the hydroxy substituent on the cyclopentanyl ring is in the CIS configuration relative to the bicyclic substituent, Y3, Y7, Y8 and Y9 are each independently nitrogen or a CH group, Q is NH2, halogen or hydrogen, and Z is hydrogen, halogen, or NH2; or a pharmaceutically-acceptable salt thereof, and to their use as immunosuppressants.

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