Carbocyclic fused cyclic amines as inhibitors of the...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/40 (2006.01) A61K 31/47 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2627426

The invention is concerned with novel carbocyclyl fused cyclic amines of formula (I) wherein A, X1 to X3, Y1 to Y3, Z, R1, R2, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.

La présente invention concerne des nouvelles amines cycliques fusionnées à un carbocyclyle de formule (I) dans laquelle A, X1 à X3, Y1 à Y3, Z, R1, R2, m et n sont tels que définis dans la description et dans les revendications, de même que leurs sels physiologiquement acceptables. Ces composés inhibent le facteur de la coagulation Xa et ils peuvent être utilisés en tant que médicaments.

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