Carbocyclic nucleosides containing bicyclic rings,...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/00 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07C 215/44 (2006.01) C07C 275/50 (2006.01) C07D 239/46 (2006.01) C07D 239/48 (2006.01) C07D 239/50 (2006.01) C07D 239/54 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 487/04 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01) C07F 9/547 (2006.01) C07F 9/6512 (2006.01) C07F 9/6561 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2099712

Carbocyclic nucleosides containing bicyclic rings. oligonucleotides therefrom. process for their preparation. their use and intermediates Abstract Compounds of the formulae I and Ia and their racemates Image (I), Image (Ia). in which A is -CH2- or -CH2CH2-, R1 is hydrogen or a protective group, R2 is hydrogen or a protective group or a radical forming a phosphorus-containing nucleotide bridge group and B is a purine or pyrimidine radical or an analogue thereof, can be used as antiviral active ingredients or for the preparation of biologically active oligonucleotides.

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