Carbohydrate binding domain containing fusion proteins for...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 19/00 (2006.01) A01N 25/24 (2006.01) A01N 25/26 (2006.01) A01N 25/28 (2006.01) A61K 9/16 (2006.01) A61K 47/38 (2006.01) A61L 15/32 (2006.01) A61L 15/44 (2006.01) A61L 27/22 (2006.01) A61L 27/54 (2006.01) C07K 14/195 (2006.01) C07K 14/37 (2006.01) C07K 16/00 (2006.01) D21H 17/22 (2006.01)

Patent

CA 2458392

A pharmaceutical or agrochemical composition or kit of parts comprises (1) a micro-particle or micro-capsule comprising at least one pharmaceutical or agrochemical benefit agent and (2) a fusion protein which comprises a first binding domain which is a carbohydrate binding domain and at least one additional binding domain capable of binding to (a) a ligand or specific site which forms part of a living organism, or (b) said microcapsule or micro- particle, wherein the first or second binding domain is capable of binding to said microcapsule or microparticle. The fusion protein itself may also be used for therapeutic or agrochemical purposes.

L'invention concerne une composition pharmaceutique ou agrochimique ou un kit d'éléments comprenant (1) une microparticule ou une microcapsule comprenant au moins un agent avantageux sur le plan pharmaceutique ou agrochimique et 2) une protéine de fusion comprenant un premier domaine de liaison qui est un domaine de liaison à un hydrate de carbone, et au moins un domaine de liaison supplémentaire capable d'une liaison avec (a) un ligand ou un site spécifique faisant partie d'un organisme vivant, ou (b) ladite microcapsule ou ladite microparticule, le premier ou le second domaine de liaison étant capable d'une liaison avec ladite microcapsule ou ladite microparticule. La protéine de fusion elle-même peut également être utilisée pour des besoins thérapeutiques ou agrochimiques.

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