Carbohydrate deficient transferrin (cdt)-specific...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/18 (2006.01) C12P 21/08 (2006.01) G01N 33/536 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2432942

The present invention relates to antibodies which, in aqueous solution, selectively bind to a transferrin- homologous carbohydrate deficient transferrin (CDT) without the latter needing to be bound to a- solid phase. CDT is characterized by at least one of the two oligosaccharide chains which are normally bound to Asn 413 and/or Asn 611 of transferrin being entirely or substantially entirely lacking.

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