Carbohydrate-lipid constructs and their use in preventing or...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/10 (2006.01) A61K 47/48 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01) C07H 15/04 (2006.01) C07H 15/06 (2006.01)

Patent

CA 2685269

The invention relates to selected carbohydrate-lipid constructs and their use as mimics of ligands for receptors expressed by a virus. In particular, the invention relates to the use of selected carbohydrate-lipid constructs in methods of inhibiting virus infection and/or promoting clearance of virus from infected subjects. Carbohydrate-lipid constructs selected for use in these methods where the virus is Human Immunodeficiency Virus (HIV) are provided.

L'invention concerne des produits de synthèse d'hydrates de carbone et de lipides et l'utilisation de ces derniers comme mimétiques de ligands de récepteurs exprimés par un virus. L'invention se rapporte en particulier à l'utilisation de produits de synthèse d'hydrates de carbone et de lipides choisis selon des procédés qui permettent d'inhiber une infection virale et/ou de favoriser la clairance virale chez des sujets infectés. L'invention porte également sur des produits de synthèse d'hydrates de carbone et de lipides choisis pour être utilisés selon les procédés précités dans le cas où le virus est le virus d'immunodéficience humaine (VIH).

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