C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 73/04 (2006.01) A61K 9/14 (2006.01) A61K 47/34 (2006.01) A61K 47/40 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C08B 37/00 (2006.01) C08B 37/16 (2006.01) C08G 73/02 (2006.01) C08G 73/06 (2006.01) C12N 15/87 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2476769
This application discloses compositions of carbohydrate-modified polymers, such as polyethylenimine modified with cyclodextrin moieties, for carrying drugs and other active agents, such as nucleic acids. Compositions are also disclosed of carbohydrate-modified polymer carriers that release such agents under controlled conditions. The invention also discloses compositions of carbohydrate-modified polymer carriers that are coupled to biorecognition molecules for targeting the delivery of drugs to their site of action.
La présente invention concerne des compositions de polymères à base d'hydrates de carbone modifiés, tels que de la polyéthylèneimine modifiée avec des fractions de cyclodextrine, servant au transport de médicaments et d'autres agents actifs, tels que des acides nucléiques. L'invention concerne également des compositions de vecteurs polymères à base d'hydrates de carbone modifiés libérant ces agents dans des conditions contrôlées. L'invention concerne également des compositions de vecteurs polymères à base d'hydrates de carbone modifiés, associés à des molécules de bioreconnaissance, servant à cibler l'administration de médicaments vers leur site d'action.
Bellocq Nathalie C.
Cheng Jianjun
Davis Mark E.
Hwang Pun Suzie
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Insert Therapeutics Inc.
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