C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 9/00 (2006.01) A61P 15/10 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 471/00 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2437715
Compounds of the general structural formula (I) and use of the compounds and salts and solvates thereof, as therapeutic agents. In particular, the invention relates to compounds that are potent and selective inhibitors of cyclic guanosine 3', 5'-monophosphate specific phosphodiesterase (cGMP- specific PDE), in particular PDE5, and have utility in a variety of therapeutic areas wherein such inhibition is considered beneficial, including the treatment of cardiovascular disorders and erectile dysfunction.
L'invention concerne des composés de la formule de structure générale suivante, et l'utilisation de ces composés ainsi que de leurs sels et solvates en tant qu'agents thérapeutiques.
Bombrun Agnes
Bouillot Anne
Dodic Nerina
Gosmini Romain Luc Marie
Orme Mark W.
Lilly Icos Llc
Ridout & Maybee Llp
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