Carbonylamino pyrrolopyrazoles, potent kinase inhibitors

Details Carbonylamino pyrrolopyrazoles, potent kinase inhibitors Carbonylamino pyrrolopyrazoles, potent kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4162 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2634381

Carbonylamino Pyrrolopyrazole compounds of formula (I), compositions including these compounds and methods of their use are provided. Preferred compounds of formula (I) have activity as protein kinase inhibitors, including as inhibitors of PAK4.

La présente invention concerne des composés de carbonylamino-pyrrolopyrazole de formule I, des compositions comprenant ces composés et des procédés pour leur utilisation. Les composés de formule I préférés ont une activité en tant qu'inhibiteurs de protéine kinase, y compris en tant qu'inhibiteurs de PAK4.

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