Carbopeptoids and carbonucleotoids

Details Carbopeptoids and carbonucleotoids Carbopeptoids and carbonucleotoids

C - Chemistry, Metallurgy

07

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C07H 7/02 (2006.01) A61K 31/70 (2006.01) C07B 61/00 (2006.01) C07D 309/08 (2006.01) C07D 309/20 (2006.01) C07D 309/24 (2006.01) C07D 407/04 (2006.01) C07F 9/655 (2006.01) C07H 11/04 (2006.01) C07H 15/18 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2214789

Librairies are synthesized with oligomeric carbopeptoids and carbonucleotoids. Carbopeptoids are oligosaccharides having carbohydrate subunits linked to one another by amide bonds. Carbonucleotoids are oligosaccharides having carbohydrate subunits linked to one another by phosphodiester bonds. Carbopeptoid librairies may be fabricated using automated polypeptide synthesizers. Carbonucleotoid librairies may be fabricated using automated polynucleotide synthesizers.

L'invention concerne des banques dont la synthèse est obtenue avec des carbopeptoïdes et des carbonucléotoïdes oligomères. Les carbopeptoïdes sont des oligosides ayant des sous-unités glucidiques reliées entre elles par des liaisons amides. Les carbonucléotoïdes sont des oligosides ayant des sous-unités glucidiques reliées entre elles par des liaisons phosphodiester. Il est possible de constituer des banques de carbopeptoïdes et de carbonucléotoïdes au moyen de synthétiseurs automatiques de polypeptides et de polynucléotides, respectivement.

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