Carbostyril derivatives

Details Carbostyril derivatives Carbostyril derivatives

C - Chemistry, Metallurgy

07

D

C07D 215/26 (2006.01) A61K 31/47 (2006.01) C07D 215/22 (2006.01) C07D 215/227 (2006.01) C07D 217/20 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2297439

The present invention provides an agent for inhibiting skin erythema and/or skin pigmentation, containing at least one selected from the group consisting of the carbostyril derivative and salt thereof represented by general formula (1), wherein R1 is a hydrogen atom, a lower alkyl group or the like; R2 is a hydrogen atom, a lower alkyl group, a lower alkoxy group or the like; R3 and R4 are lower alkyl groups which may have hydroxyl groups as substituents or the like; the carbon- carbon bond between 3- and 4-positions in the carbostyril skeleton is a single bond or double bond.

L'invention concerne un agent servant à inhiber l'érythème et/ou la pigmentation de la peau et contenant au moins un groupe sélectionné dans le groupe constitué par le dérivé de carbostyrile et son sel représenté par la formule (1), dans laquelle R<1> représente un atome d'hydrogène, un groupe alkyle inférieur etc.; R<2> représente un atome d'hydrogène, un groupe alkyl inférieur, un groupe alkoxy inférieur etc.; R<3> et R<4> représentent des groupes alkyle inférieur pouvant posséder des groupes hydroxy en tant que substituants etc.; la liaison carbone-carbone entre les positions 3 et 4 du squelette de carbostyrile est une liaison simple ou une liaison double.

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