Carbostyril derivatives and serotonin reuptake inhibitors...

Details Carbostyril derivatives and serotonin reuptake inhibitors... Carbostyril derivatives and serotonin reuptake inhibitors...

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61K 31/137 (2006.01) A61K 31/165 (2006.01) A61K 31/381 (2006.01) A61K 31/495 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2716966

The pharmaceutical composition of the present invention comprises (1) a carbostyril derivative and (2) a serotonin reuptake inhibitor in a pharmaceutically acceptable carrier. The carbostyril derivative may be aripiprazole or a metabolite thereof, which is a dopamine-serotonin system stabilizer. The serotonin reuptake inhibitor may be fluoxetine, duloxetine, venlafaxine, milnacipran, citalopram, fluvoxamine, paroxetine, sertraline or escitalopram. The pharmaceutical composition of the present invention is useful for treating patients with mood disorders, particularly depression or major depressive disorder.

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