Carboxamide compounds and methods for using the same

Details Carboxamide compounds and methods for using the same Carboxamide compounds and methods for using the same

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/501 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2750835

Disclosed are carboxamide compounds as well as pharmaceutical compositions and methods of use. One embodiment is a compound having the structure (I) in which R1, R2, R3, R4, T, p, q, w and x are as described herein. In certain embodiments, a compound disclosed herein activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.

L'invention porte sur des composés carboxamides ainsi que sur des compositions pharmaceutiques et sur des procédés d'utilisation. Un mode de réalisation consiste en un composé ayant la structure (I) dans laquelle R1, R2, R3, R4, T, p, q, w et x sont tels que décrits présentement. Dans certains modes de réalisation, un composé décrit présentement active la voie AMPK et peut être utilisé pour traiter des troubles et des états liés au métabolisme.

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