Carboxamide-heteroaryl derivatives for the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2716385

Novel heterocyclic compounds of the formula (I) wherein D is formula (A) or formula (B) wherein R1, R2, E', E", E"', Y", Y", G', G", G"' and G"' have the meaning of claim 1, are activators of glucokinase and can be used for the prevention and/or treatment of Diabetes Typ 1 and 2, obesity, neuropathy and/or nephropa-thy.

L'invention concerne de nouveaux composés hétérocycliques de formule (I). Dans ladite formule, D est un composé d'une formule dont R1, R2, E`, E', E'`, Y', Y'`, G`, G', G``` et G'` ont la signification indiquée dans la revendication 1. Ces composés hétérocycliques sont des activateurs de la glucokinase et peuvent être utilisés pour la préparation et/ou le traitement du diabète des types 1 et 2, de l'obésité, de la neuropathie et/ou de la néphropathie.

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