Carboxamide modified polyamine chelators and radioactive...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/00 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) A61K 51/10 (2006.01) C07B 59/00 (2006.01) C07D 257/02 (2006.01) C07D 403/10 (2006.01) C07F 5/00 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) G01N 33/60 (2006.01) A61K 43/00 (1990.01)

Patent

CA 2134092

A group of functionalized polyaminocarboxamide modified chelators that form complexes with rare earth-type metal ions are disclosed. The complexes, covalently attached to an antibody or antibody fragment, can be used for therapeutic and/or diag- nostic purposes.

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