Carboximidamide derivatives

Details Carboximidamide derivatives Carboximidamide derivatives

C - Chemistry, Metallurgy

07

D

167/179, 260/277

C07D 213/58 (2006.01) C07C 257/18 (2006.01) C07C 335/32 (2006.01) C07D 213/78 (2006.01) C07D 213/81 (2006.01) C07D 215/54 (2006.01) C07D 241/24 (2006.01) C07D 307/54 (2006.01) C07D 307/68 (2006.01) C07D 333/24 (2006.01) C07D 333/38 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2006734

Disclosed are novel carboximidamide derivatives represented by the following formula. Image (A) [wherein B is Image (in which X or H or Cl), Image , Image , Image , Image , Image , Image or H3C-S-, R''' is alkyl, nitroxyalkyl, optionally substituted phenyl, 2,6-dimethoxy-3-pyridyl or Image (in which R2 is alkyl, aryl, nitroxyl, aralkoxy, hydroxyl or hydrogen, a is an integer of 1-3 and R3 is optionally substituted phenyl, phenylthio or thiophenyl) when B is Image or R''' is phenylethyl or nitroethyl when B is one of the others]. These compounds are useful as pharmaceutical agents. Also disclosed are N-cyano- pyridinecarboximidate compounds represented by the following formula (II) Image (II) (wherein X is H or Cl and R' is alkyl) which are useful as intermediates for preparing of N-cyano- N'-substituted-pyridinecarboximidamide derivatives.

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