Carboxyethylated cyclodextrin polysulfates useful as...

Details Carboxyethylated cyclodextrin polysulfates useful as... Carboxyethylated cyclodextrin polysulfates useful as...

C - Chemistry, Metallurgy

08

B

C08B 37/16 (2006.01) A61K 31/724 (2006.01) A61P 7/02 (2006.01) A61P 19/02 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2738018

This invention relates to novel .beta.-cyclodextrin polysulfate compounds comprising from one to three 2- carboxyethyl substituents, and at least two sulfates groups per glucopyranose unit, which are useful as active ingredients for the treatment and/or prophylaxis of degenerative joint diseases, osteoarthritis, articular rheumatism, arthrosis or degenerative arthritis, or for the treatment of heparin-induced thrombocytopenia, or for cartilage repair or connective tissue repair.

Cette invention porte sur de nouveaux composés polysulfates de ß-cyclodextrine comprenant de un à trois substituants 2-carboxyéthyles et au moins deux groupes sulfates par unité glucopyranose, lesquels sont utiles comme ingrédients actifs pour le traitement et/ou la prophylaxie de maladie articulaires dégénératives, de l'ostéoarthrite, du rhumatisme articulaire, de l'arthrose ou de l'arthrite dégénérative, ou pour le traitement de la thrombocytopénie induite par l'héparine, ou pour la réparation de cartilage ou la réparation de tissu conjonctif.

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