C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/292, 260/237
C07D 295/14 (2006.01) C07D 207/27 (2006.01) C07D 209/44 (2006.01) C07D 211/34 (2006.01) C07D 211/46 (2006.01) C07D 211/70 (2006.01) C07D 211/74 (2006.01) C07D 213/80 (2006.01) C07D 217/04 (2006.01) C07D 295/073 (2006.01) C07D 295/096 (2006.01) C07D 295/112 (2006.01) C07D 295/135 (2006.01) C07D 295/155 (2006.01) C07D 295/192 (2006.01) C07D 317/22 (2006.01) C07D 473/08 (2006.01) C07D 491/10 (2006.01)
Patent
CA 1176246
ABSTRACT OF THE DISCLOSURE Compounds of general formula I Image ,(I) wherein R1 and R2 represent alkyl or cycloalkyl groups or together with the nitrogen atom to which they are attached, represent a cyclic imino group, R2 represents a hydrogen or a halogen atom, an optionally substituted hydroxy, mercapto, amino, carboxy or aminocarbonyl group, or a nitro, alkanoyl, aminosulfonyl, trifluoromethyl or cyano group, R4 represents a hydrogen atom or an alkyl group. R5 represents a hydrogen or a halogen atom or an alkyl group, A represents a bond or an optionally substituted methylene, ethylene or vinylidene group, B represents a methylene or ethylene group optionally substituted by an alkyl group and W represents a hydrogen or a halogen atom, a cyano, alkanoyl or nitro group, an optionally substituted amino or aminocarbonyl group. a carboxy group or an ester thereof, a formyl group or an acetal thereof or an optionally substituted alkyl group); and salts thereof formed with acids and bases. Processes for the preparation of the new compounds as well as pharmaceutical compositions containing them are also objects of this invention. The new compounds show valuable pharmaceutical properties, especially effects on intermediary metabolism and a blood-sugar lowering activity.
393789
Grell Wolfgang
Griss Gerhart
Hurnaus Rudolf
Kahling Joachim
Kaubisch Nikolaus
Fetherstonhaugh & Co.
Thomae (dr. Karl) Gesellschaft Mit Beschrankter Haftung
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