Carboxylic acid derivatives as ip antagonists

Details Carboxylic acid derivatives as ip antagonists Carboxylic acid derivatives as ip antagonists

C - Chemistry, Metallurgy

07

C

C07C 271/22 (2006.01) A61K 31/325 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) A61P 7/04 (2006.01) C07C 311/08 (2006.01) C07C 311/21 (2006.01) C07D 209/08 (2006.01) C07D 209/12 (2006.01) C07D 215/14 (2006.01) C07D 235/18 (2006.01) C07D 263/56 (2006.01) C07D 307/12 (2006.01) C07D 307/80 (2006.01) C07D 309/04 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2401502

This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula (see formula I) wherein R1, R2, and R3 are each independently in each occurrence aryl or heteroaryl, R4 is -COOH or tetrazolyl, A, B, m, n, and r are as defined in the specification; or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds, processes for their preparation and their use as therapeutic agents.

L'invention concerne des composés qui sont, en règle générale, des antagonistes des récepteurs IP et qui correspondent à la Formule, dans laquelle R?1¿, R?2¿ et R?3¿ sont chacun, dans chaque cas et de façon indépendante, aryle ou hétéroaryle, R?4¿ est -COOH ou tétrazolyl, A, B, m, n, et r sont définis dans la spécification; ou des isomères individuels et des mélanges racémiques ou non racémiques des isomères ou leurs sels ou solvates pharmaceutiquement acceptables. L'invention concerne également des compositions pharmaceutiques contenant ces composés et des procédés de leur préparation et de leur utilisation en tant qu'agents thérapeutiques.

Affiliated with

Also associated with

Rating

Carboxylic acid derivatives as ip antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carboxylic acid derivatives as ip antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carboxylic acid derivatives as ip antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1401708